AVISAR™ System

The AVISAR™ System represents a quantum leap forward in providing a sensitive technology for detecting respiratory infections and other metabolic diseases.

The AV-BreathTest™ is based on the presence of the enzyme, urease, which is found in many bacterial species that cause lung infections, such as Mycobacterium tuberculosis.
The AV-BreathTest™ uses a solution containing13C-urea, AV-U13, that is ready for administration with the nebulizing device.
The AVISAR SPEC™ laser spectrometer incorporates major design advances that have resulted in a highly portable, battery operated detection device that will have enormous utility in point-of-care settings.
The AVISAR SPEC™ is a rugged, portable device that rapidly measures breath13CO2/12CO2 isotopic ratios.
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Global Unmet Need for Better TB Diagnostics


  • Tuberculosis (TB) continues to be a major worldwide health problem with over 9 million new cases in 2012 and 1.3 million deaths.

  • TB is highly contagious making timely diagnosis critical not only for patient treatment, but also for implementation of infection control measures to prevent further spread.

  • The universal challenge that limits the successful treatment of these diverse patient groups is the lack of non-sputum point-of-care technologies that can rapidly detect when a patient has a respiratory infection that requires further triage.

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Meet Our Team

David S. Joseph
Co-Founder, President, CEO & Chairman
Graham S. Timmins, Ph.D.
Chief Science Advisor
Elizabeth A. Perkett, M.D.
Chief Medical Officer
Carol LaRotonda
David Karshmer
VP, Technology Development
John Maynard
VP, Engineering
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Latest from the Newsroom

Tuberculosis Case Prompts Search for Patient’s Fellow Airline Passengers

June 8th, 2015|

Health officials are trying to identify people who may have come into contact with a woman who flew from India to Chicago in April and had a type of tuberculosis […]

Study: Elderly Patients Have 35% Higher Risk of Death After Contracting Infections in ICUs

January 8th, 2015|

Elderly patients in hospital intensive care units have a higher risk of mortality if they develop an infection during their stay, according to a study published Monday in the American […]

Tuberculosis Rates Still High in the UK

October 4th, 2014|

Tuberculosis rates in the UK are still unacceptably high. Public Health England notes in its annual UK report that 7892 cases of tuberculosis were notified in 2013, a decrease from […]

If Tuberculosis Spreads…

July 8th, 2014|

ATLANTA — DRUG-RESISTANT tuberculosis is on the rise. The World Health Organization reports around 500,000 new drug-resistant cases each year. Fewer than half of patients with extensively drug-resistant tuberculosis will […]