David S. Joseph
President & CEO, Co-Founder
Mr. Joseph is a Co-Founder of Avisa Pharma with forty years of healthcare and life science management; co-founder and CEO of five companies in medical technology, biomaterials and biopharmaceuticals. Mr. Joseph served as Chairman and CEO of Othera Pharmaceuticals and co-founder of Orthovita Inc, a company he also where he also served as President and CEO. Stryker Corporation acquired Orthovita in 2012. Prior to Orthovita, Mr. Joseph co-founded two medical device companies: Surgical Laser Technologies, Inc., which became public in 1989 and SITE Microsurgical Systems, which was acquired by Johnson & Johnson Corporation in 1983. He also has over 15 years of executive healthcare management experience. Mr. Joseph received the Greater Philadelphia Venture Group’s Raymond Rafferty Entrepreneurial Excellence Award in May 2005 for having founded four successful venture-backed companies and for his influence on the ophthalmic and medical technology industries.
His past and present board appointments include Animas Corporation, a diabetes insulin pump technology acquired by Johnson & Johnson in 2006; Aspire Bariatics Inc., an obesity technology company; Seamless Medical Systems, a patient engagement and media company. HTH Worldwide, a privately held internet travel health insurance and information company; Morphotek Inc., a privately held biotechnology company acquired by Eisai Pharmaceuticals in 2007; TLC Vision, a leader in Lasik surgery centers; Managed Healthcare Services, Inc.; The Jackson Laboratory Board of Governing Trustees; and King’s College Board of Directors.
Senior Vice President, Product Development
Mr. Karshmer is a biomedical engineer and designer with over twenty years of experience in the development of innovative products and services for the healthcare markets. He has worked on products ranging from pediatric infusion pumps to bioreactors for cell line growth. Mr. Karshmer brings a deep interest in user-centered design and innovative technology to his work. He founded the IDEO Healthcare practice and has developed medical devices, products, and services for leading diversified healthcare companies including Advanced Cardiovascular Systems, Medtronic, Therox, Advanced Tissue Sciences, 3M Healthcare, Inhale, Eli Lilly, IVAC, Abbott Laboratories, Baxter Healthcare, Heartstream, Pfizer, Nellcor, Cerus and GlaxoWellcome. His work has produced numerous patents and design awards in fields ranging from insulin delivery to integrated cardiovascular health management. Mr. Karshmer holds degrees from University College London, and the University of California at San Diego.
Vice President, Finance
Prior to joining Avisa, Mr. Culler was Vice President, Finance & Operations at xF Technologies, a venture-backed renewable chemistry start-up. Before his work at xF Technologies, Mr. Culler was a Principal at Sun Mountain Capital, one of the largest venture capital firms headquartered in the Southwest. Prior to Sun Mountain Capital, Mr. Culler participated in financings totaling over $2 billion as a Senior Analyst in the Private Equity Placements Group of Bank of America’s investment banking business in New York City. Matt has a BBA in Finance with honors from the University of Texas at Austin.